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Case 221 - Discussion

Hematopathology Case

 

Plasma Cell Myeloma

  • The tumor cells in this cases show abundant intracytoplasmic crystals, which can mimic histiocytes. However, compared to the histiocytes, the neoplastic plasma cells have higher N/C ratio, atypical nuclear morphology, blue-cytoplasm, and intracytoplasmic crystals in stead of vacuoles.