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Case 262 - Discussion

Hematopathology Case

 

CD20

CD3

CD138

Kappa

 
Lambda  

 

Plasma Cell Myeloma

  • The marrow smears show monotonous small lymphocytic or plasmacytic cells. The nuclei are round and eccentric in some cells. The chromatin is condensed.

  • The trephine biopsy shows sheets of small cells, which closely mimic lymphocytes and don't show plasmacytoid features as seen on the smears.