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Case 287 - Discussion

Hematopathology Case

 

CD1a

CD45

CD68

MAA

MEL-A

S100

 

SOX10

 

 

Diagnosis: Metastatic melanoma

Discussion: The patient had a history of melanoma with multiple organ involvement. The tumor cells in the lymph node show interfollicular infiltrative pattern and cells closely resemble histiocytes or lymphoma cells. However, histiocytes typically do not have distinct cytoplasmic borders.