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Case 290

Hematopathology Case

Clinical information:

 

A 63-year-old female presented with pancytopenia. Multiple bone marrow biopsies revealed extensive marrow necrosis with crystals initially. A last marrow biopsy showed viable leukemia cells focally.

 

 

 

 

 

Bone marrow aspirate smear of initial biopsies. Wright-Giemsa, 4

Bone marrow aspirate smear of initial biopsies. Wright-Giemsa, 4

 

 

Bone marrow aspirate smear of initial biopsies. Wright-Giemsa, 20

Bone marrow aspirate smear of initial biopsies. Wright-Giemsa, 100

 

 

Bone marrow core of initial biopsies. HE, 4

Bone marrow core of initial biopsies. HE, 10

 

 

 

Bone marrow core of initial biopsies. HE, 40

 

 

 

 

Repeated Marrow Biopsy

 

 

Bone marrow core of a repeated biopsy. HE, 4

Bone marrow core of a repeated biopsy. HE, 40

 

 

 

 

Click here for diagnosis and discussion

 

Case from: Department of Pathology, University of Colorado Denver, Aurora, Co