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Case 6 - Discussion

Surgical Pathology Case

 

HHV8, 20

 

Kaposi Sarcoma
  • HIV+ patients

  • Typically irregular patchy infiltrate

  • Less well-formed vascular structures in fascicules, slip-like lumen

  • Endothelial cells with overt atypia

  • Extravasated RBCs and hyaline globules

  • Endothelial cells: HHV8+, Ulex europaeus-, and factor VIIIRA-

  • HHV8 associated lesions:

    • Kaposi sarcoma

    • Multicentric Castleman disease

    • Primary effusion lymphoma