Differences Between Endosalpingiosis, Borderline Tumor and Adenocarcinoma

Of Gynecologic Peritoneal Wash Cytology

 

 

Uploaded: 2007-08-19,  Updated: 2007-08-19

 

 

Endosalpingiosis

 Borderline Tumor

Adenocarcinoma
Patterns Tightly cohesive aggregates, single layer Cohesive Less cohesive
Papillae Simple, non-branching Larger, often branching, smooth borders Smaller, irregular borders
Cells Small, orderly, uniform Small, overlapping, less uniform, well-defined cell borders, single Larger, more single cells, syncitial and indistinct cell borders
Atypia Little or none Slight to moderate Moderate to marked
Cilia Present Occasionally present Extremely rare
Psammoma body No significant difference No significant difference No significant difference
Cytoplasm Scant, basophilic Scant, basophilic, few vacuoles Abundant, often vacuoles
Nuclei High N/C ratio, eccentric, round to oval, smooth nuclear membrane High N/C ratio, monomorphic, smooth or slightly irregular nuclear membrane Less N/C ratio, irregular nuclear membrane
Chromatin Fine, even Less dense More dense
Nucleolus Inconspicuous Inconspicuous or invisible Prominent
Mitoses None None or rare Often present

 

Reference
 

  • The art and science of cytopathology. Richard M Demay, MD. 1996
  Summarized by Zenggang Pan, MD, PhD