Case 2 - Discussion



Epidermal Nevus / Verrucous epidermal nevi

  • Mostly present at birth or develop during early infancy; grow slowly during childhood and reach stable size at adolescence;

  • Hyperplasia of epidermis, verrucous papules that coalesce to form well-demarcated, skin colored to brown, papillomatous plaques;

  • Lesions may be localized or diffuse. Linear configurations are common, especially on the limbs, and may follow skin tension lines;

  • Histology: hyperkeratosis, acanthosis and papillomatosis.

  • Extensive verrucous epidermal nevi may be associated with the epidermal nevus syndrome, a disease complex consisting of various developmental abnormalities of the skin and eyes, as well as the central nervous, skeletal, cardiovascular, and urogenital systems.



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  • Hohenleutner U, Landthaler M. Laser therapy of verrucous epidermal naevi. Clin Exp Dermatol 1993;18(2):124-7.