Case 27

 
Clinical Information
 

An 82-year-old man presented with a 1-cm raised dermal nodule on the right foot that has been present for unknown duration. There was no history of melanoma or  any other pigmented skin lesion. Biopsied skin showed a well-circumscribed white, firm dermal nodule.

 
 

 

   
 

Low magnification.

 
   
 

Higher magnification.

 
   
 

HMB-45: Negative.

 
   
 

Melan-A: Negative.

 
   
 

S-100 protein: Weakly positive.

 
   
 

MITF: Strongly positive nuclear stain.

 
     
 

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