Case 39 - Discussion


   
HMB45, 20 MART1, 20
MITF, 20 S100, 20
   

 

 

Malignant melanoma, Clark's Level V

 
 
 
  Malignant Melanoma Parameters
  • Clinical: Tumor Location: Left dorsal forearm (part B)
  • Sex, age: Male, 81 years.
  • Macroscopic: Excision
  • Tumor size: Greatest dimension: 0.8
  • Histologic subtype: Superficial spreading
  • Tumor thickness: 5.8 mm
  • Clark's Level: V (in subcutaneous fat)
  • Ulceration: Absent
  • Mitotic rate: >6 per mm^2 (high)
  • Angiolymphatic invasion: Absent
  • Host inflammation: Moderate
  • Regression: Absent
  • Microscopic satellites: Present
  • Precursor lesion: Absent
  • Margin status: Positive
  • Pathologic Stage (pTNM) (Micro staging): pT4a, pNX, pMX