Case 43 - Discussion

Uploaded: 2007-06-06, Updated: 2007-06-06


   
 

INVASIVE MODERATELY DIFFERENTIATED SQUAMOUS CELL CARCINOMA WITH FOCAL PAGETOID FEATURES

The squamous cell carcinoma shows focal areas with scattered malignant cells with clear cytoplasm weakly positive for mucin, predominantly arranged around the intraepidermal portion of hair follicles and sweat glands, suggestive of pagetoid differentiation from intraepidermal portion of the sweat glands. However these cells are negative for CK7, CK20, AR, CEA, and S100.

   
   
Clinical Futures
   
Gross Findings
   
Microscopic Findings
   
Subtypes
   
Differential Diagnosis
   
Immunohistochemistry Straining
   
Election Microscopy
   
Cytogenetics
   
Treatment and Prognosis
   
Reference