Case 68 - Discussion

Uploaded: 2007-11-28, Updated: 2007-11-28



Glomus Tumor

  • Clinical: Solitary glomus tumors usually have paroxysmal pain, which can be severe and exacerbated by pressure or temperature changes, especially cold. Hildreth sign, disappearance of pain after application of a tourniquet proximally on the arm. Love test, eliciting pain by applying pressure to a precise area with the tip of a pencil

  • Location:  most commonly in acral areas, especially subungual areas of fingers and toes

  • Gross: blue or purple, papules or nodules that can be blanched, usually smaller than 1 cm

  • Histology: Solitary glomus tumor usually appears as a well-circumscribed nodule surrounded by a rim of fibrous tissue. The tumor consists of endothelium-lined vascular spaces surrounded by clusters of glomus cells. The glomus cells are monomorphous, round or polygonal with plump nuclei and scant eosinophilic cytoplasm.