- Clinical: Benign tumor
of mammary-like anogenital glands or presumed apocrine origin.
Usually occurs in middle aged women.
- Site: Restricted
in the genitoperineal skin, eyelids, and axillae.
- Gross: small
(<1cm) red-blue dermal nodule.
- Circumscribed solid or
partly cystic dermal tumor with no connection to the surface
- Contains a central cystic
space with papillary projections. The papillae have
- Solid cellular foci are
common with more complex branching and interconnecting
- The tumor consists two cell
linings cover the stalks: outer epithelial cells and inner
myoepithelial cells. The epithelial cells are tall cuboidal
to columnar cells with pale eosinophilic cytoplasm and
- Prominent apocrine changes
are noted in areas. Mitotic count is occasionally high;
- PAS positive
diastase-resistant granules are present in the apices of the
- Differential diagnosis: