Hematopathology--Case Diagnosis

 

 

Uploaded: 2009-09-26, Updated: 2011-10-25

 
Case

Specimen

Diagnosis

1 Bone marrow aspirate Lupus Erythematosus Cell (LE Cell)
2 Bone marrow biopsy Acute promyelocytic leukemia, Hypogranular Type
3 Cervical lymph nodes Interfollicular Hodgkin Lymphoma
4 Bone marrow biopsy Acute promyelocytic leukemia, Hypergranular Type
5 Bone marrow biopsy Multiple Myeloma
6 Bone marrow biopsy Lymphoid Blast Phase of Chronic Myelogenous Leukemia
7 Bone marrow

Hairy Cell Leukemia

8 Peripheral blood smear Chronic Lymphocytic Leukemia
9 Peripheral blood smear B-Cell Prolymphocytic Leukemia
10 Bone marrow biopsy Chronic Idiopathic Myelofibrosis
11 Lymph node Anaplastic Large Cell Lymphoma
12 Colon biopsy Mantle Cell Lymphoma
13 Bone marrow biopsy Acute Monocytic Leukemia
14 Lymph node Nodular Lymphocyte Predominant Hodgkin Lymphoma
15 Lymph node

Hodgkin’s disease variant of Richter’s transformation

16 Vulva Lesion

Langerhans Cell Histiocytosis of the Vulva

17 Peripheral blood smear Chronic Monocytic Leukemia
18 Bone marrow biopsy Multiple Myeloma
19 Peripheral blood smear Acute Monocytic Leukemia
20 Lymph node, inguinal Anaplastic Large Cell Lymphoma
21 Lymph node, inguinal Mantle Cell Lymphoma
22 Small Intestinal Mass

Enteropathy-Type T Cell Lymphoma

23 Bone marrow biopsy

Acute promyelocytic leukemia, Hypergranular Type

24 Bone marrow biopsy

Acute myeloid leukemia

25 Bone marrow biopsy ??
26 Bone marrow Metastatic Prostate Adenocarcinoma
27 Lymph node, inguinal Anaplastic Large Cell Lymphoma
28 Splenic mass Follicular lymphoma of Spleen
29 Nasal mass Diffuse large B-cell lymphoma
30 Peripheral blood smear T-cell Granular cell leukemia
31 Skin biopsy Cutaneous T-Cell Lymphoma
32 Lymph node, axillary

Angioimmunoblastic T-cell lymphoma

33 Lymph node, mediastinal Follicular Lymphoma
34 Testicular mass Diffuse Large B-Cell Lymphoma of Testicle
35 Lymph node, retroperitoneum Small B-cell lymphoma
36 Lymph node, axillary Small lymphocytic lymphoma/Chronic lymphocytic leukemia
37 Thyroid mass Hodgkin Lymphoma, Nodular Sclerosing Type
38 Lymph node, submandibular Nodular Lymphocyte Predominant Hodgkin Lymphoma
39 Lymph node, cervical Hodgkin Lymphoma, Nodular Sclerosing Type
40 Peripheral blood smear

Howell Jolly Bodies

41 Gastroesophageal junction Plasmablastic lymphoma
42 Bone marrow biopsy Plasmablastic lymphoma
43 Lymph node, supraclavicular Granular cell sarcoma
44 Peripheral blood smear Basophilic Stippling and Howell-Jolly Bodies
45 Peripheral blood smear

Pending

46 Lymph node, cervical Sarcoidosis and Asteroid Body
47 Subcutaneous lesion Anaplastic large cell lymphoma, small cell variant
48 Lymph node, mesenteric Diffuse Large B-Cell Lymphoma, Anaplastic Type (CD30+)
49 Gallbladder lesion

Mastocytosis

50 Subcutaneous lesion

Anaplastic Large Cell Lymphoma (ALCL), cutaneous type

51 Mediastinal mass Follicular dendritic cell sarcoma
52 Small intestinal lesion Extra nodal marginal zone lymphoma
53 Lymph node, inguinal T-cell lymphoma, nodal
54 Liver lesion Mastocytosis
55 Lymph node, mediastinal Castleman's disease
56 Lymph node, cervical Classic Hodgkin Lymphoma, Nodular Sclerosis Type
57 Skin lesion Cutaneous Mastocytosis
58 Lymph node, axillary Metastatic desmoplastic melanoma
59 Lymph node, axillary

Angioimmunoblastic T-cell lymphoma

60 Lymph node, axillary Diffuse large B-cell lymphoma
61 Small intestine Follicular Lymphoma
62 Soft tissue mass, right arm

Kimura Disease

63 Lymph node, cervical Mantle cell lymphoma
64 Hemoglobin electrophoresis ?
65 Bone marrow biopsy Angiosarcoma, metastatic
66 Serum protein electrophoresis Light chain myeloma
67 Bone marrow biopsy Mastocytosis
68 Lymph node, inguinal Nodular Lymphocyte Predominant Hodgkin Lymphoma
69 Lymph node, cervical Classic Hodgkin Lymphoma, Nodular Sclerosis Type
70 Lymph node, cervical Diffuse Large B-Cell Lymphoma, transformed from CLL/SLL
71 Rectum Mantle cell lymphoma
72 Skin, back Primary Cutaneous Follicular Center Lymphoma
73 Lymph node, inguinal Metastatic Merkel cell carcinoma.
74 Lymph node, inguinal Mantle cell lymphoma
75 Minor salivary gland lesion Marginal zone lymphoma
76 Lymph node, cervical Classic Hodgkin Lymphoma
77 Pancreas Primary myeloid sarcoma
78 Epidural mass Diffuse Large B-Cell Lymphoma
79 Lymph node, axillary Myeloid sarcoma
80 Lymph node, inguinal Diffuse large B-cell lymphoma, transformed from follicular lymphoma
81 Bone marrow biopsy Acute myeloid leukemia
82 Lymph node, abdominal Myeloid sarcoma
83 Colon Diffuse Large B-cell lymphoma of the colon
84 Lymph node, axillary Lymphadenopathy associated with tattoo
85 Lymph node, axillary Marginal zone lymphoma, nodal
86 Lymph node, abdominal Castleman's disease
87 Peripheral blood smear Mantle Cell Lymphoma Involving Peripheral Blood
88 Lymph node, cervical Small lymphocytic lymphoma
89 Occipital skull lesion

Langerhans Cell Histiocytosis (Eosinophilic Granuloma)

90 Lymph node, postauricular Anaplastic Large T/Null-Cell Lymphoma
91 Lymph node, terminal ileum Burkitt Lymphoma
92 Lymph node, cervical Precursor T-Cell Lymphoblastic Leukemia
93 Peripheral blood smear Infectious mononucleosis
94 Peripheral blood smear Acute Megakaryoblastic Leukemia
95 Mediastinal mass Precursor T-Cell Lymphoblastic Leukemia
96 Bone marrow biopsy Gaucher's Disease
97 Bone marrow biopsy Metastatic Poorly Differentiated Neuroblastoma
98 Lymph node, abdominal Burkitt Lymphoma
99 Ileocecal mass Burkitt Lymphoma
100 Systemic metastasis Systemic Hodgkin's Lymphoma
101 Bone marrow biopsy Burkitt Lymphoma
102 Testicular mass Rosai-Dorfman Disease
103 Lymph node, cervical Rosai-Dorfman Disease
104 Gastroesophageal junction Mantle Cell Lymphoma
105 Splenic mass Hepatosplenic Gamma-Delta T-Cell Lymphoma 
106 Splenic mass Splenic Marginal Zone Lymphoma
107 Peripheral blood/CSF Mantle Cell Lymphoma
108 Bone marrow biopsy Histoplasmosis
109 Lymph node, cervical Alveolar rhabdomyosarcoma, metastatic 
110 Skin Follicular lymphoma, primary or metastatic
111 Bone marrow biopsy BCG Granuloma in Bone Marrow
112 Kidney Follicular lymphoma
113 Lymph node, submandibular Large B-cell lymphoma
114 Testicular mass Large B-cell lymphoma
115 Lymph node, cervical Toxoplasma lymphadenitis
116 Skin Primary Cutaneous CD30+ Lymphoproliferative Disorder
117 Lymph node, cervical Anaplastic large cell lymphoma
118 Humerus, proximal  Large B-cell lymphoma
119 Lymph node, inguinal Palisaded Myofibroblastoma
120 Bone marrow biopsy Systemic mastocytosis
121 Lymph node, cervical Peripheral T-Cell lymphoma, Lymphoepithelioid Variant (Lennert Lymphoma)
122 Skin NK cell lymphoma of skin
123 Eye lid Myeloid sarcoma, monoblastic
124 Bone marrow Parvovirus infection of erythroid cells in bone marrow
125 Lymph node, axillary Cat scratch disease
126 Lymph node, axillary Cat scratch disease
127 Lymph node, axillary Peipheral T-cell lymphoma involving lymph node
128

Orbit mass

Mantle Cell Lymphoma
129 Lymph node, cervical Lymphadenopathy associated with infectious mononucleosis
130 Soft tissue, arm Kimura Disease
131 Peripheral blood Plasma Cell Leukemia, IgA type, with Flame Cells
132 Bone marrow Copper Deficiency 
133 Lymph node, cervical Mycobacterium avium complex (MAC)
134 Spleen Littoral cell hemangioma
135 Lymph node, axillary Peipheral T-cell lymphoma involving lymph node
136 Lymph node, axillary Peipheral T-cell lymphoma involving lymph node
137 Lymph node Mantle cell lymphoma
137 Spleen Mantle cell lymphoma
138 Thyroid mass Diffuse large B-cell lymphoma of thyroid
139 Lymph node Marginal zone lymphoma with follicular colonization
140 Lymph node, cervical Myeloid sarcoma (h/o M4)
141 Lymph node, obturator Metallosis of lymph node
142 Lymph node, inguinal HIV lymphadenitis, acute phase
143 Lymph node, cervical HIV lymphadenitis, chronic phase
144 Lymph node Castleman disease
145 Lymph node T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
146 Nasal mass Nasal T/NK lymphoma
147 Lymph node Histiocytic sarcoma
148 Lymph node, colon Extracavitary HHV8+ large B-cell lymphoma
149 Lymph node, axillary Intranodal melanocytic nevocellular inclusions (nodal nevi)
150 Lymph node, axillary Metastatic Lobular Carcinoma of Breast
151 Lymph node Extramedullary Hematopoiesis
151 Spleen Extramedullary Hematopoiesis
152 Lymph node, cervical Atrophy of Lymph Node due to Sickle Cell Disease
153 Peripheral blood smear Transient Myeloproliferative Disorder (TMD) 
154 Brain Myeloid Sarcoma
155 Lymph node, axillary Mantle Zone Hyperplasia
156 Spleen Amyloidosis of Spleen
157 Spleen Marginal Zone Hyperplasia 
158 Spleen ?
159 Lymph node, axillary Metastatic Lobular Carcinoma of Breast
160 Lymph node Extracavitary large B-cell lymphoma
161 Lymph node, axillary Benign Mammary Glandular Inclusions in Lymph Node
162 Lymph node, cervical Rosai-Dorfman Disease
163 Lymph node, cervical SLL with Large B-Cell Transformation, metastatic squamous cell carcinoma
164

Lymph node, mesenteric

Granulomas in lymph node
165 Lymph node, axillary Mantle Zone Hyperplasia
166 Lymph node Necrotizing granulomas
167 Mediastinal mass

Classic Hodgkin Lymphoma in Lymphoepithelial Cyst

168 Lymph node Diffuse large B-cell lymphoma
169 Lymph node Vascular proliferation
170 Stomach Large B-cell lymphoma
171 Lymph node

Metastatic Thyroid Medullary Carcinoma

172 Lymph node

Classic Hodgkin Lymphoma, Lymphocyte Depletion Type

173 Bone marrow

Mastocytosis

174 Breast Metastatic Melanoma
175 Lymph node Diffuse large B-cell lymphoma
176 Lymph node T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
177 Blood clot, aneurysm Diffuse large B-cell lymphoma
178 Lymph node

Classic Hodgkin Lymphoma, Mixed Cellularity Subtype

179 Lymph node

Sinusoidal CD30+ Large B-Cell Lymphoma

180 Lymph node

ALK Positive Large B-Cell Lymphoma

181 Soft tissue, chest wall Rosai-Dorfman Disease
182 Lymph node

Metallosis of Lymph node

183 Bone Rosai-Dorfman Disease of Bone
184 Brain Primary CNS lymphoma
185 Oral cavity

Plasmablastic Lymphoma of Oral Cavity

186 Spleen

Niemann-Pick Disease

187 Spleen

Plasma Cell Myeloma Involving Spleen

188 Lymph node

Plasma Cell Myeloma Involving Lymph Node

189 Lung Lymphomatoid Granulomatosis
190 Skin Mastocytosis
191 Lymph node, inguinal Anaplastic large cell lymphoma, nodal
192 Lymph node, cervical Mastocytosis, nodal
193 Oral mucosa lesion Extranodal marginal zone lymphoma, MALT type
194 Skin lesion Classic Hodgkin lymphoma, primary cutaneous
195 Lymph node, Cervical Toxoplasmosis, nodal
196 Lymph node, Cervical Kikuchi disease
197 Lymph node, cervical Systemic lupus erythematosus (SLE) lymphadenopathy
198 Lymph node, cervical Kimura disease, nodal
199 Tonsil lesion Epstein-Barr virus infection
200 Lymph node, cervical Castleman disease
201 Peripheral blood smear T-cell prolymphocytic leukemia (T-PLL)
202 Bone lesion Langerhans cell histiocytosis
203 Bone marrow biopsy Hodgkin lymphoma, metastatic
204 Bone marrow biopsy Plasma cell myeloma
205 Bone marrow biopsy Plasma cell myeloma
206 Peripheral blood smear Follicular cell lymphoma involving peripheral blood
207 Peripheral blood smear Plasma cell leukemia
208 Peripheral blood smear T-cell prolymphocytic leukemia (T-PLL)
209 Peripheral blood smear Mantle cell leukemia
210 Peripheral blood smear Sezary cell leukemia
211 Peripheral blood smear Sezary cell leukemia
212 Peripheral blood smear Follicular cell lymphoma involving peripheral blood
213 Lymph node Plasmacytoid dendritic cell nodule
214 Peripheral blood smear Chronic lymphocytic leukemia
215 Lymph node, cervical Anaplastic Large Cell Lymphoma
216 Peripheral blood smear B-Cell Prolymphocytic Leukemia
217 Bone marrow biopsy Hairy Cell Leukemia
218 Lymph node, axillary Nodular Lymphocyte Predominant Hodgkin Lymphoma 
219 Bone marrow biopsy Plasma Cell Myeloma
220 Peripheral blood smear B-Cell Acute Lymphoblastic Leukemia
221 Bone marrow biopsy Plasma Cell Myeloma
222 Lymph node, inguinal Follicular Lymphoma with Marginal Zone Differentiation
223 Bone marrow biopsy Plasma Cell Myeloma
224 Bone marrow biopsy Megaloblastic Anemia
225 Lymph node, cervical Classic Hodgkin Lymphoma, Mixed Cellularity Type
226 Lymph node, inguinal Follicular Lymphoma with sclerosis
227 Cecal mass Burkitt Lymphoma
228 Lymph node, cervical Follicular Lymphoma with signet-ring cell features
229 Lymph node, inguinal Peripheral T-Cell lymphoma, Lymphoepithelioid Variant (Lennert Lymphoma)