CLINICAL INFORMATION

Bone marrow biopsy and aspirate

PERIPHERAL BLOOD SMEAR AND DIFFERENTIATION

    WBC, 43.7 K/uL 

       NEUTR,   2.0%,      

       LYMPH,    21%,      

       MONO,    6.0%,      

       EOSIN,   1.0%,     

       BLASTS, 20.0%,     

    RBC, 4.19 M/uL 

    HGB, 11.1 g/dL

    HCT, 31.7 %  

    MCV,   76 fL   

    MCH, 26.5 pg

    RDW, 15.5 %  

    PLT,   12 K/uL

Wright-Giemsa, 100×

Wright-Giemsa, 100×

Wright-Giemsa, 100×

BONE MARROW ASPIRATE AND TOUCH IMPRINT

Wright-Giemsa, 100×

Wright-Giemsa, 100×

Wright-Giemsa, 100×

BONE MARROW CORE BIOPSY AND CLOT

HE, 20×

MPO, 40×

CD34, 40×

FLOW CYTOMETRY

CYTOGENETICS

PML/RARA fusion in 98% of the interphase cells, and these results are positive for the t(15;17)(q22;q11.2).

Click here for diagnosis and case discussion.

Source: Department of Pathology, Creighton University Medical Center, Omaha, NE

Photo: Zenggang Pan

Discussion: Zenggang Pan