Case 2

Hematopathology Case
 

CLINICAL INFORMATION

 

Bone marrow biopsy and aspirate

 

 

PERIPHERAL BLOOD SMEAR AND DIFFERENTIATION

 

    WBC, 43.7 K/uL 

       NEUTR,   2.0%,      

       LYMPH,    21%,      

       MONO,    6.0%,      

       EOSIN,   1.0%,     

       BLASTS, 20.0%,     

    RBC, 4.19 M/uL 

    HGB, 11.1 g/dL

    HCT, 31.7 %  

    MCV,   76 fL   

    MCH, 26.5 pg

    RDW, 15.5 %  

    PLT,   12 K/uL

 

 

Wright-Giemsa, 100

Wright-Giemsa, 100
 

 

Wright-Giemsa, 100

Wright-Giemsa, 100
 

 

Wright-Giemsa, 100

 

BONE MARROW ASPIRATE AND TOUCH IMPRINT

   
 

 

Wright-Giemsa, 100

Wright-Giemsa, 100
 

 

Wright-Giemsa, 100

Wright-Giemsa, 100
 

 
 

Wright-Giemsa, 100

 
 

BONE MARROW CORE BIOPSY AND CLOT

 
 

 

HE, 20

HE, 40
 

 

MPO, 40

CD117, 40
 

 
 

CD34, 40

 
 

FLOW CYTOMETRY

     

CYTOGENETICS

 

PML/RARA fusion in 98% of the interphase cells, and these results are positive for the t(15;17)(q22;q11.2).

     
     
 

Click here for diagnosis and case discussion.

 

Source: Department of Pathology, Creighton University Medical Center, Omaha, NE

Photo: Zenggang Pan

Discussion: Zenggang Pan