Case 14

Hematopathology Cases
 

CLINICAL INFORMATION

 

39 year-old male who initially developed an enlarged lymph node in the left lower anterior cervical chain in 2005 that persisted for several years. He reports that he has had night sweats for about 3 years off and on but that they have now become more frequent and severe and are to the point that they are drenching and requires him to change his clothes often at night.  He also reports fatigue, nausea, arthralgias, and some occasional rashes between the digits on his hands.  He has not had any weight loss or fevers.  He also interestingly recalls that at age 19, he developed a lymph node in the groin that was biopsied and he was told was normal.  On 5/15/07 CT scan showed lymphadenopathy up to 3.9 cm involving the left supraclavicular region extending into the left axilla.  An excisional left supraclavicular lymph node biopsy was performed on 6/8/07.

GROSS DESCRIPTION

 

The specimen consists of a piece of tan/red soft nodule measuring 3.5 x 3.5 x 1.2 cm.

     
 
 

HE, 2

HE, 4

 
 

HE, 10

HE, 10

 
 

HE, 20

HE, 20

 
 

HE, 20

HE, 20

 
 

HE, 20

HE, 40

 
 

HE, 40

HE, 40

 
 

HE, 40

HE, 40

 
 

HE, 60

HE, 60

 
 

HE, 40

HE, touch prep, 100

 
  Wright-Giemsa, touch prep, 100 Wright-Giemsa, touch prep, 100
     
 

Click here for diagnosis and case discussion.

 

Source: Department of Pathology, Creighton University Medical Center, Omaha, NE

Photo: Zenggang Pan

Discussion: Zenggang Pan