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Case 66 - Discussion

Uploaded: 2008-10-24, Updated: 2008-10-24

Light Chain Myeloma
(Bence Jones Myeloma)
  • 15-20% of all myeloma cases.
  • More malignant course compared to classic myeloma.
  • Extremely rapid doubling time.
  • Tendency for more osteolytic lesions.
  • Increased hypercalcemia.
  • Higher incidence of renal failure
  • Higher incidence of amyloidosis and plasma cell leukemia.
  • Renal failure, principle cause of death.
  • Lambda LCM has 3x worse prognosis than kappa LCM.