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Case 146 - Discussion

Uploaded: 2010-10-21, Updated: 2010-10-21

 

CD3

CD56

Granuzyme B

Ki67

 

EBER

 

 

 

Nasal T/NK Cell Lymphoma

  • More common in Asian
  • HE: massive necrosis, prominent vascular proliferation, angiocentric, epitheliotropism
  • CD2+, sCD3-, cCD3+, CD56+, TIA-1+
  • EBV+ in most cases
  • TCR gene rearrangement -
  • Associated with hemophagocytic syndrome