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Case 197 - Discussion

Uploaded: 2011-09-22, Updated: 2011-09-22


Systemic Lupus Erythematosus Lymphadenopaty

  • 60% of SLE show lymphadenopathy, mostly cervical and mesenteric lymph nodes

  • Histology:

  • Follicular hyperplasia with or without an interfollicular expansion

  • Numerous plasma cells in germinal centers and the medullary cords

  • Large areas of coagulative necrosis with ghost lymphocytes, abundant karyorrhectic debris, and histiocytes. Neutrophils are scant or present

  • Hemotoxin bodies