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Case 209 - Discussion

Uploaded: 2011-09-22, Updated: 2011-09-22

 

Circulating Mantle Cell Lymphoma Cells

  • An absolute lymphocytosis has been reported in MCL.
  • The circulating MCL cells are small, mature-appearing with condensed chromatin that closed resemble the cells in CLL. However, generally the MCL cells are slightly larger than CLL cells with more variants of cell size and morphology and more nuclear irregularities. Some MCL cells are small with round nuclei and condensed chromatin, whereas others are medium in size with slightly dispersed chromatin, more cytoplasm, or a distinct central nucleolus