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The Expression of Cytokeratin in Human Tumors |
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Uploaded: 2007-11-06, Updated: 2007-11-12 |
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AE1/3 |
34βE12 |
CK5/6 |
CK7 |
CK8/18 |
CK20 |
CDX2 |
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Adrenal cortical carcinoma |
− |
− |
0 |
0 |
− |
0 |
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Bile duct, Cholangiocarcinoma |
+ |
+/− |
14 |
93 |
+ |
43 |
25 |
CEA+ |
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Bladder, urothelial carcinoma |
+ |
+/− |
62 |
88 |
+ |
29 |
100 |
CK17+ |
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Breast carcinoma, ductal/lobular |
+ |
+/− |
− |
96 |
+ |
0 |
GCDFP15+ |
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Cervix, squamous cell carcinoma |
+ |
−/+ |
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87 |
+ |
0 |
CEA+ |
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Colorectal adenocarcinoma |
+ |
− |
0 |
5 |
+ |
100 |
99 |
CEA+ |
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Endometrial adenocarcinoma |
+ |
+/− |
50 |
100 |
+ |
0 |
CEA− |
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Gastric adenocarcinoma |
+ |
− |
− |
38 |
+ |
50 |
77 |
CEA+ |
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Hemangioendothelioma, epithelioid |
+/− |
− |
− |
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− |
CD31, CD34, F8 + |
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Liver, fibrolamellar hepatoma |
−/+ |
− |
+ |
+ |
− |
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Liver, hepatoma |
− |
− |
14 |
− |
+ |
− |
CEA− |
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Lung, adenocarcinoma |
+ |
+/− |
5 |
100 |
+ |
10 |
TTF1+ |
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Lung, small cell carcinoma, |
+ |
− |
− |
43 |
+ |
0 |
TTF1+ |
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Lung, squamous cell carcinoma |
+ |
+ |
− |
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0 |
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Merkel cell carcinoma |
+ |
− |
− |
− |
+ |
78 |
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Mesothelioma |
+ |
76 |
65 |
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0 |
WT1+, Calrectinin+ |
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Neuroendocrine tumor |
+ |
− |
10 |
56 |
+ |
6 |
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Ovarian carcinoma, mucinous |
+ |
− |
−/+ |
100 |
+ |
+ |
64 |
Vim+ |
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Ovarian carcinoma, non-mucinous |
+ |
+/− |
100 |
+ |
− |
Vim+, WT1+, |
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Paget's disease, apocrine origin |
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+ |
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GCDFP15+, CEA+ | ||
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Pancreatic adenocarcinoma |
+ |
+/− |
38 |
92 |
+ |
62 |
32 |
CEA+ |
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Prostate adenocarcinoma |
+ |
− |
0 |
−/+ |
+ |
0 |
4 |
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Renal, chromophobe RCC |
+ |
− |
0 |
+ |
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0 |
CD117+, Vim−, RCC+ |
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Renal, clear cell carcinoma |
+ |
− |
0 |
− |
+ |
0 |
RCC+, Vim+, CD10+ |
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Renal, Oncocytoma |
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+Scattered |
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0 |
CD117+ |
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Renal, papillary RCC |
+ |
− |
0 |
+ |
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0 |
RCC+, CD10+, Vim+/- |
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Salivary gland, all tumors |
+ |
+/− |
93 |
100 |
+ |
0 |
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Thymus, thymoma |
+ |
+/− |
100 |
0 |
+ |
0 |
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Thyroid, all tumors |
+ |
+/− |
− |
98 |
+ |
+/− |
4 |
TTF1+ |
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Thyroid, papillary carcinoma |
+ |
+/− |
− |
+ |
+ |
− |
− |
TTF1+, CK19+, Vim+ |
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| Summarized by: Zenggang Pan, MD, PhD |