Case 9 - Discussion

Uploaded: 2007-01-14, Updated: 2007-12-07

Drug induced perivascular chronic dermatitis

Clues to Drug Reactions

  • Hyperkeratosis, parakeratosis;

  • Superficial dermal edema and spongiosis;

  • Apoptotic keratinocytes or individual keratinocytic necrosis;

  • Superficial perivascular lesions with exocytosis of lymphocytes, eosinophils and/or plasma cells;

  • Endothelial swelling of vessels;

  • Nuclear dusts and red cell extravasation.

Superficial and Deep Inflammation of the Skin (8Ls+DRUGS)

  • Light reaction;

  • Lymphoma;

  • Leprosy;

  • Lues;

  • Lichen stratus;

  • Lupus erythematosus;

  • Lipidica (Necrobiosis);

  • Lepidoptera (and other arthropods)

  • Dermatophyte

  • Reticular erythmatous mucinosis;

  • Urticarial stages (BP);

  • Gyrate erythemas;

  • Scleroderma;

  • Drug reactions.