Case 32 - Discussion

Uploaded: 2007-03-12, Updated: 2007-06-22

  RIGHT UPPER LOBE OF LUNG, LOBECTOMY:
- Poorly differentiated squamous cell carcinoma.
- Maximal dimension of mass is 3.0 cm in diameter.
- Twelve regional lymph nodes negative for metastatic malignancy.
- Bronchial surgical margin and pleural margin negative for malignancy.
- No vascular permeation is identified.
- Pathologic stage: pT1, N0, MX.

Immunostains of TTF-1, CK 5/6, CK7, CK20 and CDX-2 were performed in formalin fixed paraffin embedded block B4. The malignancy is positive for CK5/6, but negative for CK7, TTF-1,CK20 and CDX-2. This immuno profile of this malignanncy is not diagnostic for lung primary. Clinical correlation is suggested.

   
Clinical Futures
   
Gross Findings
   
Microscopic Findings
   
Subtypes
   
Differential Diagnosis
   
Immunohistochemistry Straining
   
Election Microscopy
   
Cytogenetics
   
Treatment and Prognosis
   
Reference