Immunostains on block B14
Ultrastructurally, the neoplasm is composed of sheets of neoplastic
cells. The cells are made of irregularly-shaped cells containing
round to oval nuclei. These neoplastic cells have recurrent tight
junctions. The cytoplasm of these cells contain many mitochondria,
smooth endoplasmic reticulum and numerous dense core granules
surrounded by a plasma membrane. These granules are round and vary
in size from 0.102 to 0.239 micros. These are consistent with
neurosecretory granules seen in neuroendocrine tumors.
(Interpretation performed by Dr. JW / WH)
Normal male chromosome complement: 46,XY.
Cytogenetic analysis did not reveal any evidence of a consistent
detectable numerical or structural chromosomal anomaly at this band