Case 175

Surgical Pathology Case


  A 48-year-old female slowly developed swelling and pain over left knee for 12 months. A curette was made for pathology diagnosis.



Radiographs demonstrated a destructive radiolucent lesion of the medial femoral condyle of the distal third of the left femur. The lesion extended to the subcondylar bone. The interface of the tumor and surrounding cancellous bone was well delineated. There was no evidence of an internal reactive shell or border, neither was there any periosteal reaction. MRI of the distal femur and knee showed a large soft tissue mass extending from the interosseous tumor in a posterior direction. The mass partially filled the popliteal space. A chest CT scan revealed bilateral pulmonary numerous metastasis.


X-Ray, left knee

HE, 4


HE, 20

HE, 20


HE, 40

HE, 40


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Source: Department of Pathology, Creighton University Medical Center, Omaha, NE

Photo: Zenggang Pan

Discussion: Zenggang Pan