Case 211 - Discussion

Uploaded: 2008-05-06, Updated: 2008-05-06

  • Immunohistochemistry Stainings:

    • CD34 +

    • CD99 − (r/o synovial)

    • BCL2 − (r/o solitary fibrous tumor)

    • Desmin − (r/o leiomyosarcomas)

    • S-100 − (r/o neural tumors)

    • CD117 − (r/o GIST)

    • CK AE1/AE3 −

    • Ki-67 − (> 100/hpf)

  • Cytogenetic Studies

    • Positive for t(17;22)(q21;q13), COL1A1/PDGFB fusion.

 

 

 

CD34  
   
Dermatofibrosarcoma Protuberans (DFSP)

The Key Features

 

CLINICAL FEATURES

 

GROSS FINDINGS

 

MICROSCOPIC FINDINGS

 

SUBTYPES

 

DIFFERENTIAL DIAGNOSES

 

IMMUNOHISTOCHEMISTRY AND SPECIAL STAINS

 

ELECTRON MICROSCOPIC FINDINGS

 

CYTOGENETIC STUDIES

 

TREATMENT AND PROGNOSIS

 

REFERENCES