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Case 273

Surgical Pathology Case
 

CLINICAL INFORMATION

  A 40-year-old previously healthy female reported to her physician for recent onset of abnormal uterine bleeding. A physical examination revealed an enlarged uterus of approximately 16-week gestational size. An endometrial curettage revealed invasive adenocarcinoma with signet-ring cells features. A systemic workup revealed a primary appendiceal tumor with extensive involvement of the ileum, cecum, omentum, and uterus, including the cervix.
     
 
  Endometrium. HE, 20 Endometrium. HE, 20
   
  Endometrium. HE, 40  
 
 

Uterine cervix. HE, 2

Uterine cervix. HE, 10

 
 

Uterine cervix. HE, 20

Uterine cervix. HE, 40

 
 

Uterine cervix. HE, 40

Myometrium. HE, 40

 
 

Appendix. HE, 10

Appendix. HE, 20

     
 

Click here for diagnosis and discussion.

 

Source: Dr. Ronald Leonard. Cytocheck Laboratory, LLC. Parsons, Kansas 67357, USA

Department of Pathology, Creighton University Medical Center, Omaha, NE

Photo: Zenggang Pan

Discussion: Zenggang Pan