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Case 273

Surgical Pathology Case
 

CLINICAL INFORMATION

  A 40-year-old previously healthy female reported to her physician for recent onset of abnormal uterine bleeding. A physical examination revealed an enlarged uterus of approximately 16-week gestational size. An endometrial curettage revealed invasive adenocarcinoma with signet-ring cells features. A systemic workup revealed a primary appendiceal tumor with extensive involvement of the ileum, cecum, omentum, and uterus, including the cervix.
     
 
  Endometrium. HE, 20× Endometrium. HE, 20×
   
  Endometrium. HE, 40×  
 
 

Uterine cervix. HE, 2×

Uterine cervix. HE, 10×

 
 

Uterine cervix. HE, 20×

Uterine cervix. HE, 40×

 
 

Uterine cervix. HE, 40×

Myometrium. HE, 40×

 
 

Appendix. HE, 10×

Appendix. HE, 20×

     
 

Click here for diagnosis and discussion.

 

Source: Dr. Ronald Leonard. Cytocheck Laboratory, LLC. Parsons, Kansas 67357, USA

Department of Pathology, Creighton University Medical Center, Omaha, NE

Photo: Zenggang Pan

Discussion: Zenggang Pan