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Case 278 - Discussion

Uploaded: 2008-12-29, Updated: 2009-01-05

Fibrocongestive Splenomegaly (Congestive Splenomegaly)

  • Gross: large and firm, fibrous thickening of the capsule.

  • Micro:

    • Marked dilation of the vein and sinuses.

    • Fibrosis of the red pulp with accumulation of hemosiderin-laden microphages.

    • Focal hemorrhage with sclerosiderotic nodule and iron deposit in the connective tissue (Gamma-Gandy body).

    • The white pulp and lymphoid follicle are unremarkable.

REFERENCES

  • Rosai and Ackerman's Surgical Pathology, 9th edition.