Also called monomorphic adenoma
female predilection, mostly in parotid gland.
often cystic, relatively small.
solid, trabecular or tubular growth of epithelial cells; peripheral palisading;
abundant basal lamina material around and within the tumor
nests; occasional acinar cells, squamous
whorls or keratinization; no invasion, mesenchymal component or myxoid matrix.
multiple dermal cylindroma and 16q abnormality.
IPX: ductal cells
-keratin, alpha-1-antichymotrypsin, CEA, S100 (alpha
subunit); basaloid cells - vimentin, actin, S100 (beta
adenoma, a variant of basal cell adenoma, bilayered strands
or ribbons of columnar cells sperated by loose
well-vascularized stroma. Mostly in minor salivary glands.