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Case 309

Surgical Pathology Case
 

CLINICAL INFORMATION

  68 years old male, previously healthy. Recent onset of brief intermittent jerks of the right arm. This progressed to difficulty speaking and with simple tasks such as brushing his teeth, and eventually to generalized clonic jerking movements in all extremities and total aphasia. Negative HIV, heavy mental screen, liver function, and toxicology. EEG noncontributory. CT of the brain showed mild atrophy  with no mass or hydrocephalus. He died two months later.

GROSS DESCRIPTION

 

The brain weighs 1155 grams, grossly normal with only a faint tan discoloration of the white matter, most prominent in the occipital lobe.

     
 
 

HE, 10

HE, 10

 
 

HE, 10

HE, 10

 
 

HE, 20

HE, 20

     
 

Click here for diagnosis and discussion.

 

Source: AFIP, HQAP-2001-II-2

Photo: Zenggang Pan

Discussion: Zenggang Pan