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Case 382 - Discussion

Uploaded: 2010-03-11, Updated: 2010-03-11

Metastatic Melanoma

  • Dyscohesive plasmacytoid cells, occasional binucleation (Bug-eye cell). Patient had a history of melanoma on the back 7 years ago.

  • DDX: lymphocytes. The tumor cells in this cases are a little more cohesive than lymphocytes. Binucleation is extremely rare in lymphocytes. I only saw one; one day, a heme tech knocked at my door excitedly and showed me a PB smear with one pretty binucleated lymphocyte. This was the only one she saw in many years.