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Case 416 - Discussion

Uploaded: 2010-08-05, Updated: 2010-08-05


Tyrosine Crystalloids in Pleomorphic Adenoma


  • Tyrosine crystalloids are reported in 1.5 - 21% of salivary gland tumors, preferentially in pleomorphic adenomas

  • Also seen in malignant salivary gland tumors, including carcinoma ex pleomorphic adenoma, adenoid cystic carcinoma, and terminal duct adenocarcinoma.

  • Maybe be formed from substances secreted by myoepithelial cells and subsequently assembled extracellularly

  • Morphology: striking petal-shaped floral arrangements

Rereference: Arch Pathol Lab Med, 2005, 129: 101-102