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Case 442 - Discussion

Uploaded: 2010-10-21, Updated: 2010-10-21

 

Papillary Thyroid Carcinoma, Follicular Variant

Diagnostic Criteria,  Follicular Variant of PTC
  • Major Criteria

    • Enlarged overlapping nuclei

    • Ground glass nuclei

    • Irregular nuclei with small nucleoli near nuclear membrane

    • Nuclear grooves

    • Intranuclear cytoplasmic invaginations

  • Minor Criteria

    • Irregular contours of follicles

    • Enlongated follicles

    • Dark staining colloid

    • Scalloping of colloid

    • Multinucleated giant cells within follicles