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Case 445 - Discussion

Uploaded: 2010-10-24, Updated: 2010-10-24


Focal nodular hyperplasia

  • Young females, not associated with OCPs, may associated with hemangioma

  • Asymptomatic, incidental, no hemoperitoneum

  • Gross: solitary, central scar, no cirrhosis, no capsule

  • HE:

    • Normal-appearing hepatocytes in nodules partly surrounded by fibrous bands

    • Bile ductures and thick-walled vessels in fibrous stroma

    • Cholestasis, copper, cholate stasis

  • ER/PR-