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Case 479 - Discussion

Uploaded: 2011-03-11, Updated: 20111-03-11

 

Diagnosis: Squamous cell carcinoma ex-inverted papilloma.

 

Sinonasal Papilloma (Schneiderian Papilloma)

  • Inverted type (47%)

    • Lateral nasal wall

    • Respiratory/non-keratinizing squamous epithelium

    • Transmigrating neutrophils

    • HPV6/11 most common, EBV-

    • Often recur, 10% malignancy

  • Septal/Exophytic type (50%)

    • Exophytic squamous growth, residual goblet cells

    • Malignancy rare

  • Cylindrical/Oncocytic/Columnar cell type (3%)

    • Lateral nasal wall

    • Multilayered, ciliated columnar cells, goblet cells, intra-epithelial mucin cyst

    • <10% malignant