(polytetrafluoroethylene) is an inert,
resinous polymer of tetrafluoroethylene.
In the early 1980s, Teflon was used to
provide long-term tissue bulk in the deficient areas, particularly
in the periurethral area for urinary incontinence, the posterior
pharynx for velopharyngeal insufficiency, and the true vocal fold
for vocal cord paralysis. By the early 1990s, however, as a result
of its implication in granuloma formation, tissue augmentation
with Teflon diminished dramatically.
Histologically, Teflon granuloma is characterized
by activated macrophages, multinucleated giant cells, and dense
collagenous tissue, usually 3 to 6 months after injection.