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Case 480 - Discussion

Uploaded: 2011-03-11, Updated: 2011-03-11

 

Teflon Granuloma

  • Teflon (polytetrafluoroethylene) is an inert, resinous polymer of tetrafluoroethylene.

  • In the early 1980s, Teflon  was used to provide long-term tissue bulk in the deficient areas, particularly in the periurethral area for urinary incontinence, the posterior pharynx for velopharyngeal insufficiency, and the true vocal fold for vocal cord paralysis. By the early 1990s, however, as a result of its implication in granuloma formation, tissue augmentation with Teflon diminished dramatically.

  • Histologically, Teflon granuloma is characterized by activated macrophages, multinucleated giant cells, and dense collagenous tissue, usually 3 to 6 months after injection.