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Case 522 - Discussion

Uploaded: 2011-09-04, Updated: 2011-91-04

 

Progressive Multifocal Leukoencephalopathy (PML)

  • Immunocompromised, AIDS

  • Papova virus –JC strain, SV40 T antigen +

  • White matter, demyelinating

  • Intranuclear amphophilic ground glass inclusions in astrocytes and oligodendrocytes

  • Bizarre, quasi-neoplastic astrocytes